Безопасно. Совместимый. Минимальный риск для грудного вскармливания и ребёнка.
Витамин B12 существует естественным образом в молоке при концентрации 1 нанограммы / мл (Sauberan 2019; диапазон: от 0,3 до 3 нг / мл). Материнское добавление с цианокобаламином едва повышает уровень молока у хорошо питаемых женщин (Sandberg 1981), но это улучшает уровень у женщин с низким социально-экономическим статусом (Sneed 1981). Концентрация в молозиве в 28 раз выше, чем у зрелого молока. Продукты, богатые витамином B12, - это мясо, офтал, яйца, молочные продукты, лосось, сардины, моллюски и укрепленные хлопья.
С различным и сбалансированным диетом не требуется витаминные добавки, но дефицит B12 наблюдался в плазме и молоке женщин со строгими вегетарианскими диетами (веганами), малабсорбционными заболеваниями (например, болезнью Крона, целиааааа), бариатрическая операция Плохой статус питания, пагубная анемия, низкий социально-экономический статус и в случаях стихийных бедствий или войн. Существует множество публикаций, показывающих, что дети из этих матерей подвергаются высокому риску заболевания из -за дефицита витамина B12, что может привести к анемии, задержке и психомоторной отсталости.
«Флэш -пастеризация», применяемая к грудному молоку матерей, которые являются ВИЧ+, не уменьшает концентрацию витамина В12.
Американская академия педиатрии: лекарства обычно совместимы с грудным вскармливанием (AAP 2001).
Список основных лекарств: совместимый с грудным вскармливанием (WHO/Unicef 2002).
| Наименование | Значение | Ед.изм. |
|---|---|---|
| Tmax | 2 - 8 | час |
| T½ | 144 | час |
| Молекулярная масса | 1344 - 2791 | Да |
| Связывание с белками | Alta - High | % |
| Соотношение М/П | 1 | - |
См. ниже информацию об этих сопутствующих препаратах:
Вегетарианская диета ◐ Умеренный риск
Альтернатив: не найдено
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Vitamin B12.
Fact Sheet for Health Professionals.
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